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Final Pre-Game Predictions and Odds

Final Pre-Game Predictions and Odds

Key Takeaways:

Introduction to the Matchup
The San Francisco 49ers and Seattle Seahawks are set to face off in a highly anticipated divisional round matchup in the NFL playoffs. The two NFC West rivals will battle it out at Lumen Field in Seattle, with the winner advancing to the NFC Championship game. The stakes are high, and both teams are looking to make a deep run in the postseason. The 49ers have already pulled off an upset in the wild-card round, defeating the Philadelphia Eagles 23-19, and are looking to continue their momentum.

Regular Season Meetings
The 49ers and Seahawks split their two meetings during the regular season. The Seahawks got the best of the 49ers in their last meeting, winning 13-3 on January 3 to clinch home-field advantage throughout the postseason. However, the 49ers won the season opener 17-13 on September 7, 2025. The two teams have a long history of competition, and this matchup is expected to be a closely contested and intense game.

Expert Predictions
Football experts and analysts have weighed in with their predictions for the game. Some, such as Tyler Dragon and Christopher Bumbaca, are picking the Seahawks to win, while others, such as Jon Hoefling and Lorenzo Reyes, are favoring the 49ers. The predictions are split, with some experts citing the Seahawks’ home-field advantage and strong defense, while others point to the 49ers’ momentum and potent offense. The experts’ picks are as follows: USA TODAY Sports’ Tyler Dragon and Christopher Bumbaca are picking the Seahawks, while Jon Hoefling, Jordan Mendoza, Lorenzo Reyes, and Blake Schuster are picking the 49ers.

Odds and Betting Information
The current odds have the Seahawks as 7-point favorites, with a moneyline of -300 and an over/under of 44 points. The 49ers are listed as +240 underdogs. It’s worth noting that gambling involves risk, and individuals should only bet with funds they can comfortably afford to lose. The odds and betting information are subject to change, and it’s always a good idea to check the latest lines and odds before making a bet.

Conclusion and Final Thoughts
The matchup between the 49ers and Seahawks is shaping up to be a thrilling and closely contested game. Both teams have the talent and determination to make a deep run in the postseason, and this game will be a crucial test for both squads. With the expert predictions split and the odds favoring the Seahawks, it’s anyone’s game. The 49ers will need to bring their A-game if they hope to pull off the upset and advance to the NFC Championship game. The stage is set for an exciting and intense matchup, and football fans won’t want to miss it.

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